An ACT 1 Long

[itsbiju]

Not to take anything to SoEasy's request but a route in Act 1 starting from:
Walking to the back of town to get into The Weeping Hollow (then to the Den of the Fallen if it spawns)
Continue north to Field of Misery (activate the cursed chest event and Decaying Crypt if they are there)
Teleport to the Festering Woods (activate the Eternal War Conflict and Last Stand of the Ancients quests if they were to spawns) also go Crypts of the Ancients. I don't see a reason to use Warrior's Rest anymore
Teleport to Highland's Crossing to Southern Highlands to Norther Highlands to Leoric's Hunting Ground, to Leoric's Manor to the Waypoint at the back of his manor
Teleport to Halls of Agony 2 (activate the A Stranger in Need quest if it is there)
Teleport to Halls of Agony 3
Teleport back to town to start over again.

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Since patch 2.0 gave us unlimited paragon levels, this would not be to maximize EXP farming. I believe that longer runs into different areas will drop different legendaries unless someone can say differently.